Eicosanoids
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Nuclear receptors
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Marine invertebrates
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Endothelial metabolism
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UPdates...
Jun 2017
My friend Nigel Mitchell has been described as the 'Godfather of sports nutrition'.
His first book "Fuelling the cycling revolution: Nutrition strategies and recipes
behind grand tour wins and Olympic medals" has just been published and is
rather excellent.
October 2016
Another bit of good news with the publication of our new paper:
Computational modelling of the binding of arachidonic acid to the human monooxygenase CYP2J2.
Proietti G, Abelak KK, Bishop-Bailey D, Macchiarulo A, Nobeli I.
J Mol Model. 2016 Nov;22(11):279.
October 2016. Congratulations to our collaborators on the new publication
Farnesoid X Receptor and Its Ligands Inhibit the Function of Platelets.
Moraes LA, Unsworth AJ, Vaiyapuri S, Ali MS, Sasikumar P, Sage T, Flora GD, Bye AP, Kriek N, Dorchies E, Molendi-Coste O, Dombrowicz D, Staels B, Bishop-Bailey D, Gibbins JM.
Arterioscler Thromb Vasc Biol. 2016 Oct 6. pii: ATVBAHA.116.308093.
May 2016. A big thank you to all the contributors to this new publication - just out in PNAS
CYP450-derived oxylipins mediate inflammatory resolution
Derek W. Gilroy, Matthew L. Edin, Roel P. H. De Maeyer, Jonas Bystrom, Justine Newson, Fred B. Lih, Melanie Stables, Darryl C. Zeldin, and David Bishop-BaileyPNAS 2016 ; published ahead of print May 25, 2016, doi:10.1073/pnas.1521453113
January 2016
Happy New Year!
Great news of the award of an MRC CASE PhD studentship with Prof Derek Gilroy (UCL) and Dr Cali Hyde in the Bio-Analysis lab (LBIC).
December 2015
Congratulations to Ashton and Kavin who both won poster prizes at the London Vascular Biology Forum Christmas meeting
July 2015 - new publication
Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation.
Kirkby NS, Reed DM, Edin ML, Rauzi F, Mataragka S, Vojnovic I, Bishop-Bailey D, Milne GL, Longhurst H, Zeldin DC, Mitchell JA, Warner TD.FASEB J. 2015 Jul 16. pii: fj.15-275065
June 2015 - new publications:
Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins.
Thomson S, Edin ML, Lih FB, Davies M, Yaqoob MM, Hammock BD, Gilroy D, Zeldin DC, Bishop-Bailey D.
Biochem Biophys Res Commun. 2015 Jun 15. pii: S0006-291X(15)30074-7. doi: 10.1016/j.bbrc.2015.06.012.
Nuclear receptors in vascular biology.
Bishop-Bailey D.
Curr Atheroscler Rep. 2015 May;17(5):507. doi: 10.1007/s11883-015-0507-8.
Dec 2014. Just published - our new method for in vitro endothelial cell differentiation / tube formation / angiogenesis:
Title: A thin layer angiogenesis assay: a modified basement matrix assay for assessment of endothelial cell differentiation
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May 2015. Primary cell suppliers Axol labs are offering new Lab awards quarterly